Nutraceutical Revolution

Skin Supplement | Day & Night | Biphasic Nutraceutical Complex | With 21 Anti-Wrinkle Active Ingredients

X115®+PLUS3 delivers nutraceuticals to the skin:

  • Restructuring: 3 Sources of Hydrolysed Collagen, Hyaluronic Acid, Chondroitin
  • Biostimulants: Extracts of Echinacea, Centella, Pomegranate
  • Antioxidants: Lipoic Acid, Coenzyme Q10, Astaxanthin, Polyphenols
  • Vitamins: Folic Acid, Vitamin C, Vitamin E, Vitamin D, Vitamin H

In the purest, most effective, available form

For timeless skin


X115®+PLUS3 is a New Generation anti-wrinkle supplement for beautiful skin.

Nutraceutical Filler - Collagen Booster | No Needles | Renewing, Restructuring

New Formula 2022 | 3 Certified Hydrolysed Collagen Sources with High Bioavailability | 200 mg of Hyaluronic Acid | Improved Flavour and Solubility.

How X115®+PLUS3 works

The indisputable Excellence in Quantity, Quality and Effectiveness of Anti-Ageing Active Ingredients

X115®+ PLUS3 is the result of thorough research and clinical trials:

  • provides 5g of Hydrolysed Collagen and 200mg of highly bioavailable Hyaluronic Acid;
  • it contains a synergy of active ingredients to support the skin's antioxidant defences;
  • it delivers plant extracts of Echinacea and Centella Asiatica, known for their ability to stimulate skin renewal.

This nutraceutical complex stimulates and supports the synthesis of collagen, elastin and hyaluronic acid, and protects them from breakdown.

Increasing these structural macromolecules has a powerful anti-wrinkle action, keeping the skin firm, supple and protected, and improving its tone, texture, elasticity and hydration.

X115®+PLUS3 New Generation Skin Care therefore acts from within to support and stimulate collagen formation, with positive results in terms of increased skin hydration and density.

In addition, thanks to its powerful antioxidant action, it helps protect cells from oxidative stress, counteracting one of the main causes of premature ageing of the skin.


- Beauty Science at its Finest -

X115®+PLUS3 acts from within, supporting and stimulating collagen formation, with clinically proven positive results in terms of increased hydration and skin density.

  • DAY: during the day, the skin is more exposed to pro-oxidant factors (such as sunlight, pollutants and free radicals produced by the body's own metabolism). The active ingredients in the Day Vials support the skin's antioxidant defences
  • NIGHT: during the night's rest, the skin's regenerative processes are activated. Night Sachets provide collagen, hyaluronic acid and other useful nutrients for nourishing, bio-stimulating and restructuring action

To make X115®+PLUS3 even more effective, we have selected the 3 sources of hydrolysed collagen with the highest quality standards and the broadest scientific backing in terms of anti-wrinkle effectiveness:

  • Peptan ® F: Hydrolysed Fish Collagen
  • Verisol ® B: Hydrolysed Beef Collagen
  • Biocell ®: Hydrolysed Chicken Collagen

The advantages of this new formulation include:

  • high intake of biologically active peptides to stimulate collagen synthesis;
  • doubling of the hyaluronic acid content compared to X115®+PLUS2;
  • supply of chondroitin sulphate, useful for the skin and the well-being of the joints;
  • improved flavour, solubility and digestibility.

What's in X115®+PLUS3

Biphasic supplement, with dual Day & Night formulation:

  • Day vials: containing Resveratrol, α-Lipoic Acid, Coenzyme Q10, Echinacea Extracts, BioPolyphenols from Olive and Cocoa Seeds, Vitamins E, B6 and H.
  • Night Sachets: containing Marine Collagen (5g of Hydrolysed Collagen), Hyaluronic Acid (200 mg), Centella Asiatica, Vitamins C, D and Folic Acid, Zinc and Copper

IN & OUT Action Synergy

The X115® Antiage System treatment has been developed for the combined use of:

  • X115® New Generation Cream
  • X115®+PLUS New Generation Skin Care: two "Day & Night" synergistic supplements in a single product.

For a highly effective synergistic treatment.

This innovative solution exceeds the normal limits of best creams and anti-wrinkle supplements when used individually, as it provides the body with anti-ageing agents in much higher concentrations

Thanks to the exclusive synergy of cosmetic and nutraceutical active ingredients - absorbed through the skin and carried by the blood - skin treated with X115® is hit by a greater flow of anti-wrinkle active ingredients.

The result? Tangible results against the signs of ageing, which can be seen after just a few weeks.

  How it Works

Nourishing Beauty

Many people underestimate the importance of diet for the health and beauty of the skin, limiting themselves to regularly applying special anti-wrinkle creams and lotions for topical

On the other hand, many experts recognise that a properly distributed and balanced, varied and optimal diet could significantly reduce the need for anti-ageing creams and lotions.

This is because anti-wrinkle nutrients - supplied by food and absorbed by the intestine - reach the skin through blood circulation, developing their benefits from within.

For a number of reasons - e.g., unhealthy diets, unhealthy lifestyles, over-processed or preserved foods - the nutrients consumed in food may not be sufficient, or sufficiently balanced, to meet the real needs of the skin and body.

The X115® approach to skin beauty

For a comprehensive approach to the problem of skin ageing, X115® has formulated the X115®+PLUS3 nutritional support, which acts from within to nourish the deeper skin layers, where traditional anti-wrinkle creams cannot reach.

The synergistic approach with the X115® New Generation Cream provides cells and tissues with high concentrations of the basic molecules necessary to regenerate and maintain healthy skin.

This combined approach is essential since - in the same way that drugs do not perform any therapeutic action if taken at too low a dose - even creams and anti-wrinkle supplements need sufficient concentrations to produce the desired aesthetic improvement.

Much more than a "simple" anti-wrinkle supplement

Thanks to the wide range of nutraceutical actions, choosing X115®+PLUS3 eliminates the need to use multiple supplements for your well-being, resulting in significant cost savings

In particular, it is not recommended, as it is generally superfluous, to combine the product with supplements belonging to the following categories: supplements for skin and beauty; antioxidant supplements; supplements for microcirculation well-being (against tired and heavy legs); supplements for cellulite imperfections; supplements for the well-being of cartilage, joints and bones; supplements for nails and hair; supplements to strengthen the immune system; sun protection supplements.

The high concentrations of synergistic active ingredients make X115®+PLUS3 New Generation Skin Care a multi-purpose supplement:

  • Biopolyphenols and other antioxidants help the skin to defend itself against photo-aging, i.e., the harmful effects of excessive sun exposure;
  • Collagen, hyaluronic acid, vitamin C, vitamin D and zinc are important for the well-being of cartilage, joints, bones, nails and hair; Centella asiatica extracts are also important, thanks to their stimulating effect on the proliferation of fibroblasts and the production of collagen
  • Centella asiatica and vitamin C contribute to the well-being of the microcirculation, fighting the imperfections of cellulite and the heaviness of the legs (centella asiatica helps to improve the tension and elasticity of blood vessels, for this reason it is used in phytotherapy for venous insufficiency, capillary fragility, cellulite and heavy legs);
  • Echinacea, vitamin C, zinc and vitamin D support the body's natural immune system;
  • The synergy of high concentration antioxidants (biopolyphenols, coenzyme Q10, Vitamin C, Vitamin D, Lipoic Acid, Resveratrol) helps to defend the body from oxidative stress; the same substances, together with echinacea and centella extracts, are formulated for their ability to combat inflammatory processes that - in addition to being involved in the genesis and maintenance of many pathological conditions - stimulate the production of fibrotic collagen in the skin, characteristic of an elderly skin.
Integratore Collagene - Istruzioni Apertura 1
Integratore Collagene - Istruzioni Apertura 2
Integratore Collagene - Istruzioni Apertura 3


How to Use

Opening and Activation of the Biphasic Single-dose Bottle

  • Screw the cap all the way clockwise until the seal is broken, allowing the content of the cap to drop into the vial.
  • Shake vigorously for a few seconds.
  • Unscrew and drink immediately. NB: the red reservoir must remain in the cap; if it is still in the vial after opening, screw the cap back firmly and then unscrew.


Take the contents of one anti-wrinkle vial in the morning, at breakfast, and one sachet in the evening one hour before bedtime.

  • The vial's contents, to be shaken for a few seconds before use, can be swallowed directly as they are or diluted in a glass of water (approx 200ml);
  • the sachet contents should be poured into a glass of still water (approx 200ml), stirring until the product is dispersed.


Biostimulation and regeneration

The anti-wrinkle supplement X115®+PLUS3 New Generation Skin Care protects and supports the structure of the skin, stimulating it to produce the necessary molecules to regenerate itself and maintain the degree of resistance, elasticity and hydration of young skin


The classic aesthetic medicine treatments, based on the injection of high molecular weight substances into the skin (hyaluronic acid fillers, polylactic acid, etc.), are highly appreciated for their ability to smooth out wrinkles and make the skin more relaxed and youthful in the short term. However, by analysing the effects on the skin's microstructure, some critical points emerge to which modern aesthetic medicine attempts to respond by developing new treatments with a biostimulating and regenerating action

The purpose of these treatments is to encourage the skin to produce its own substances, such as hyaluronic acid and collagen of the third type (reticular), which are abundant in young skin.

The X115®+PLUS3 New Generation Skin Care supplement, in fact, combines this innovative approach of regeneration and biostimulation, providing the skin with what it needs to "heal itself":

  • supports fibroblast activity (which with ageing slows down its function), through the contribution of specific plant extracts, coenzymes and collagen;
  • supplies the skin with "building blocks" with which the cells of the dermis, the fibroblasts, produce the components they need;
  • provides useful active ingredients to support and stimulate microcirculation and antioxidant skin defences

X115®+PLUS3 New Generation Skin Care can therefore be used as an adjuvant to the latest generation of aesthetic medicine treatments or as a support to classic treatments, to address the critical issues listed above

Duration of Treatment

From the age of 25-30, the intake of X115®+PLUS3 is recommended for a period of 30-90 days, depending on individual characteristics

For example, for young and well nourished skins, 30 days of treatment is sufficient, while for mature skins, heavily stressed or exposed to strong sun exposure, a continuous intake for 90 days is recommended.

At the end of this "impact phase", we recommend switching to the basic, continuous and maintenance treatment with the X115® PRIMARY New Generation Skin Care supplement

NOTA: an abrupt interruption of X115® + PLUS treatment is not recommended; doses should be gradually reduced over 2/3 weeks.


The expiry date refers to a product that has been properly stored in unopened packaging. Store at a controlled temperature; avoid exposure to direct sunlight and sources of heat; avoid exposure to humid environments or contact with water.

During storage, the presence of a slight pale deposit at the bottom of the vial is normal. This deposit is due to the presence of plant extracts, it does not alter the quality of the product and does not mean that the product is affected. Note: Many manufacturers of supplements containing plant extracts in liquid form, filter their products to give it a clear appearance and thus improve the appeal to the consumer. However, such an operation eliminates the plant extract residues, which are still often rich in active ingredients that have not been extracted by the solvent.


Keep out of reach and sight of children under three years of age. Anti-wrinkle supplements are not intended as a substitute for a varied diet and healthy lifestyle. Do not take while pregnant, breastfeeding or under 14 years of age. Do not exceed the recommended daily dose.

Food allergies and intolerances

In terms of ingredients, the X115+Plus New Generation Skin Care supplement is:

  • GMO-free
  • BSE-TSE free
  • Gluten-free
  • Lactose-free
  • Dye-free

The product contains, among the allergens listed in Annex III bis to Directive 2007/68 and 2003/89 EC: fish products (derived from cartilage, hydrolysed marine collagen); soy products

Pharmacological interactions

If you are being treated with hypoglycemic drugs, consult your doctor prior to using the product. In this regard, it should be noted that the presence of alpha-lipoic acid in day vials produces hypoglycemic effects (lowers blood sugar); however, the product also contains about 3 grams of fructose per vial that has an opposite effect (raises blood sugar). In case of diabetes or pre-diabetes it is therefore important to consult a doctor beforehand.

In case of gastric hyperacidity, we recommend diluting the contents of the vials in natural water before consumption; if the taste is unpleasant, dilute it in water and lemon or other drinks (i. e., tea, orangeades, fruit juices) preferably without sugar.

Day Vials


Measuring cap: Maltodextrin; Vitamin E Acetate; Astaxanthin from Haematococcus pluvialis; Lipoic acid; Coenzyme Q10; Vitamin B6; silicon dioxide; Biotin. Vial: purified water; fructose; Polygonum dry extract (Polygonum cuspidatum Siebold & Zucc. root) Resveratrol 98%; Echinacea cell colture extract (Echinacea angustifolia DC. root) Echinacoside 4%; orange aroma; Cocoa dry extract (Theobroma cacao L. seeds) Polyphenols 40%; Pomegranate dry extract (Punica granatum L. fruits) Ellagic acid 20%; potassium sorbate, sodium benzoate; citric acid; Olive dry extract (Olea europaea L. leaves) Oleuropein 6%; xanthan gum.

Night Sachets


Hydrolyzed collagen (from fish Peptan F®, bovine Verisol B®, chicken cartilage Biocell Collagen®); maltodextrin; vitamin C; citric acid; berry aroma; Centella dry extract (Centella asiatica L. herba) Triterpene derivatives 10%; Sodium hyaluronate (Hyaluronic acid); natural flavoring; Zinc gluconate; Copper gluconate; sucralose; Vitamin D3; Folic acid. Allergens: Contains fish derivatives

Day Vials

Nutritional Values
1 Vial VNR*
P.olygonum cuspidatum radice e.s.
  of which resveratrol
E.chinacea angustifoglia radice e.s.
  of which echinacosid
T.heobroma cacao semi e.s.
  of which polyphenols
P.unica granatum frutti e.s.
  of which ellagic acid
O.lea euroapea frutti e.s.
  of which oleuropein
Vitamin E (Tocoferolo acetato) 15 mg 125%
Lipoic acid 12,50 mg -
Coenzyme Q10 12,50 mg -
Vitamin B6 2 mg 143%
Astaxanthin 1 mg -
Biotin 0,1 mg 200%

Sachets Night

Nutritional Values
1 Sachet VNR*
Hydrolized fish Collagen 2.500 mg -
Hydrolyzed bovine collagen 1.500 mg  
Hydrolyzed chicken collagen
  of which chondroitin sulphate
  of which hyaluronic acid
Hyaluronic acid 100 mg -
Vitamin C 300 mg 375%
C.entella asiatica, plant e.s.
  contain total triterpene derivatives
Zinc 5 mg 50%
Copper 1 mg 100%
Folic Acid 100 mcg 50%
Vitamin D3 2 mcg 40%


Frequently Asked Questions about X115® + PLUS and Collagen-based Anti-Wrinkle Supplements

Collagen is a very rich structural protein in the body, which plays a structural role in connective tissue and helps to maintain the physiological functions of the skin, but also of the cartilage and joints in general.

Collagen is largely responsible for the strength, endurance and firmness of young, healthy skin. With ageing, collagen concentrations in the skin decrease significantly.

With ageing, collagen undergoes changes that compromise its functionality. For example, collagen undergoes glycation, a chemical reaction between sugar molecules and the protein, which causes it to lose its structure and function. In addition, age, as well as long-term exposure to the sun, can cause an increase in the activity of Extracellular Matrix Metalloprotease (MMPs), which, like glycation, causes the loss of collagen structure and function. Buy online on collagen and the ability of X115® to increase it.

Hydrolysed collagen used in anti-wrinkle supplements undergoes an enzymatic digestion process to break it down into smaller molecular fragments. This results in a product that is more digestible, absorbable and effective, as well as more soluble and pleasant to taste.

Once taken, collagen is digested in the stomach and in the very first tracts of the intestine. Specific digestive enzymes then break it down into very small protein fragments, which are then absorbed by the intestine.

From the intestine, collagen peptides are transported by the blood to the sites of metabolic use. At the skin level, in particular, these peptides are used by particular cells, called fibroblasts, which when stimulated by the peptides themselves produce new collagen, elastin and hyaluronic acid.

The X115®+ Plus New Generation Skin Care anti-wrinkle supplement contains hydrolysed collagen of pharmaceutical quality type I and III, with a high content of proline, hydroxyproline and glycine, extracted from the skin of fish, farmed in compliance with current regulations and tested for the absence of heavy metal contamination.

Although more expensive than bovine or porcine collagen, fish collagen boasts greater health safety, better organoleptic characteristics and a decidedly greater amount of studies to support its specific effectiveness against wrinkles.

No, vegetable collagen is completely different from animal collagen and does not contain the amino acids necessary for the production of collagen in the human body. As a result, it is totally ineffective as an anti-wrinkle supplement.

In reality, collagen does not exist in the plant world; therefore, the extract of certain algae with a gelling action, such as agar agar, which is actually protein-free but composed of polysaccharides, is improperly called plant collagen.

Unless otherwise advised by the doctor, it is not recommended, as it is generally superfluous, to combine the product with supplements belonging to the following categories: supplements for skin and beauty; collagen supplements; hyaluronic acid supplements; antioxidant supplements; supplements for microcirculation well-being (against tired and heavy legs); supplements for cellulite imperfections; supplements for the well-being of cartilage, joints and bones; supplements for nails and hair; supplements to strengthen the immune system; sun protection supplements.

The X115®+PLUS3 Skin Supplement is designed to provide complete antioxidant-antiage protection. Combining it with other similar products could lead to an excessive intake of certain substances; in this regard, please note that an excess could be as harmful as a deficiency.

Should the product be combined with vitamin supplements, it is preferable to use medium-low dosage formulas to avoid vitamin excesses or, alternatively, to halve the recommended doses.

In general, before combining X115®+PLUS3 with other similar supplements, it is advisable to consult your doctor or pharmacist.

The anti-wrinkle supplement X115®+PLUS3 contains high-quality hydrolysed collagen type I and III extracted from fish (Tilapia and Pangasius) farmed by the French company Peptan Rousselot. All fish used for collagen extraction comes from establishments registered with the European Union for the import of edible fish, suitable for human consumption and guaranteed by health certificates signed by official veterinarians.

Due to the presence of Fish Derivatives, the product is NOT suitable for vegans and vegetarians

IMPORTANT NOTE regarding PLANT COLLAGEN: Collagen is a typically animal protein, which is not present in the plant world. That which is commonly (and improperly) called "plant collagen" is actually a mixture of fibrous and gelling substances extracted from certain algae. The most classic example is agar-agar, which is used to replace animal gelatin in vegan recipes. In any case, whatever the origin, plant collagen has no direct benefit to our skin, since it is a completely different substance to animal collagen

X115®+PLUS3 New Generation Skin Care comes in an exclusive and elegant box containing 15 vials and 15 sachets. The compositions and functional meaning of the two formulas are also different; while the active ingredients in the vials mainly act as powerful natural antioxidants, those in the sachets have a nourishing and supporting effect on the skin's trophism.

It is recommended to take the contents of one vial in the morning, at breakfast, and one sachet in the evening just before bedtime.

In fact, regenerative processes mainly occur during rest, whereas during the day the skin is more exposed to pro-oxidant factors (sun rays, pollutants, free radicals produced by body metabolism during various activities).

X115®+PLUS3 New Generation Skin Care 76 €